The objective of this program is to integrate the developed enabling technologies from the three tightly coupled programs IPD, IVS, and IAS into a multi-facet AI-XR pipeline platform system to provide valuable aids for precise clinical decision making, surgical navigation and prognosis assessment, as well as to facilitate efficient communication between various specialists at different clinical stages. We will develop two prototypes with liver cancer (hepatocellular carcinoma) and kidney cancer as case studies and further validate its efficacy on our collected multimodal clinical data and real treatment procedures by ex-vivo experiments. We will conduct clinical trials.